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    2022-09-30 00:00:02ҽѧ
    ʾܶ໼ߵ˲ȵĵ費ҪɿڣʲôԳԣΪSLEµľǸȾԵòʣֶӣշظȾ

    ϵͳԺǴSLEһ֢Խ֯Ҫ෢Ůԣˡ˺СҲᷢʽϵ͡òۼȫϵͳࡢࡢزȣڶSLE亦֮⣬һЩȽϳŻҲܹעһܽһ°~

    1 ȾᵼSLE

    ֪SLE÷Ůԣν˲𡱣ÿ쿴ϵСкġƵġ̵ġġϵĸͷⲻĶͬʱֵȾ᲻ᵼ߲

    ĿǰʹõȾΪȾֳȾȾҪɷΪȾϣȾϣżϼ㰷⣩⽫ȾΪȾм壬Ȼżϼ·żϷӦɫȾ[1]

    оƷ㰷ҩշǴۺ㰷ʵȾɴSLEһ۵㣬һЩоδͳһ

    һ74ߵIJо֣ʹȾӻSLEΣգOR=1.695Cl 0.77-3.51[2]1986Freni-Titulaer[3]ռ44֯ߺ88ߣоָʹȾ֯ķһĹԡCooper[4]۲˱¶ڶֻأ衢ˮ⡢ɱȾˣ90ΪŮԣѪӫ⿹˿ζȣʾʹȾԽڲ˿Ӱ죨0R=1.4SLEصڲ壬ڵٴ֮ǰѪ忹˿ΪԣʹùȾĽ˿˿壬ԺչΪSLEΣԿܾͻˡ

    ȻȾSLEյоõ˷񶨵Ľ1992һָʹȾSLEķͼӰ[5]һ91SLEߺ22ƤǴ߽оΪʹú͵ȾٴҲ񻯼ԤʹȾ SLEƤǴߵĽ[6]µһǰհо12Ůʿ˳36׷١ʹȾ֢֮ûйϵ͡ȾܻӲŮزķա

    ȻΪȾSLEķԹԵо˵Dzܺó߼йԵоʹȾȷʵǴ֢״߹

    ܽ˵ȾзյģSLEż롰ԡһҲDzԡȾƷѡҪЩġΪ˽ͳɱʹõĶǡ޲ƷͷƤܴ˺Ǿ͵òʧˣȻҪҪԣʱҪѡʵIJƷһҪѡ÷Ϲұ׼ĺϸƷȻԲȾõ

    2 SLEôԣ

    ܶ໼ߵ˲ȵĵ費ҪɿڣʲôԳԣΪSLEµľǸȾԵòʣֶӣշظȾǵСʵϰʱÿٽڼգξͷߣؼҲҪϹԶˮҪϴɾÿˮ̹źãȻвĻߣؼһӡ

    ôSLEߵ׸ôԣܵ˵ѭԭǣΡ֬ǡʵʳ

    ΣӦƤʼػ𺦵Ļ׵ˮˮףҪʳ

    ֬SLE߻٣θңӦó嵭ʳʳú֬϶ʳ

    ǣSLE߳ڷƤʼأ̴򲡼ۺҪʵƷٳԺߵʳ

    ʵʳʳﵰʵİģʽԽӽ嵰ʵİģʽֵԽױãΪʵʡ磺

    ٶﵰףϺ⡢ţЩ൱жʵĵʡ

    ڶĵʣƶ̶ڶҲǺʵʵʳ

    ۵ĵʣѼȵĵҲʵʵҪԴ

    ൰ףţ̡Ҳзḻʵʡ

    𺦵SLE߳дʴжʧɵ͵Ѫ֢˱벹㹻ʵס

    3 SLEߣصϳԻϳԣ

    SLEĻʯSLEյάֻоҪλ[7]֪SLEڼ伤غҪΪеĻ߼ҳǷõسԵþûôˣôص׸ϳԻϳԣһγ껹ǷֿԱȽϺã

    ϳԣΪڼάܣصķҪԡ塪ᣬܵҩлѧӰ죬һٷȷִηӰСҸҲСԺļسҷüغܻ־񿺷ܣϷûDZ˯ǰøá

    4 쳣ʲô壿

    C3Ǽ߲徭;Ҫɷ֣ѽ⡢Ŵ弶ӦC4ϵͳ;ĵ2ӣɽ鵼Ӧ8ݡC1q߲徭;ʼؿ壬SLEķչҪãɽ߸ǿ壬ǿ֢Ӧˣ9ݡ

    SLEڶ̼Ӧ𣬴IgGڣʹ߸֯٣ ʹ屻ġоʾSLEѪIgGIgAIgMڽ IgG C3 SLE߳ڴ쳣й[10]SLE߻ڣIgGߺͲC3ĽΪԣ11ݡѧ߽򵰰׺͵ͲΪжSLEԵĸָ꣬ IgGͲC3SLEϾҪֵ12]

    Ѫ岹C3C4C1qˮƽ SLE߲س̶ءѪ岹 C3C4ˮƽԽͼC1qˮƽԽߣSLE߲ԽأʾͨѪ岹 C3 C4 C1qˮƽЧԤ

    5 ʲô֢״SLEˣ

    ճУSLE߿ܻΪָԭ𸴷ָȾʹò䡢ҩʳȡܵȵȲ˲ž֢״ʵҼ쳣Dz鸴

    ֮ƽʱƣͣϢûԸơ

    ԭķȻѪߡȲԸðʲβϵͳȾȽͣҲ¡

    ³ֵѪףʵƤָ֡(ֺ)ˡλƤԭƤأղߡ״ߡƤ𡢶ԺƤѪƤ䡢ܺߵȡ

    ؽʹָ֣ؽڡؽڡϥ顢׹ؽڵʹףɰ鳿йؽڻҺ

    ѷԡ

    ڡ

    ˮİҺ

    ³ֵĵ򵰰ͻȻ࣬򳣹гֺϸ

    ϸѪСٻƶѪԣѪϸѪС塢Ѫɫصˮƽ

    ϵͳ֢״ͷʹŻ¡鴤

    6 SLEܴ¹

    ¹Ŀǰ˵ȵĻˣOur World in Dataͳݣ2022-09-30ȫѾֳ1.83ڼ¹硣࣬5522йλΡô࣬SLE߷ˣSLEܴܲ磿

    Ŀǰڽнֵ¹硣ӢϣڵѧὨӦƵĻ߶ӦýSARS-CoV-2硣߹ܵµȺΪȫܼػơдȶĻ޽ɿɽ磬ıԿζȿܻͨȺ黼ڽ֮ǰѯרҽɽ¹硣

    ˵SLEǿԽġĿǰڼسƼյԼԷڣ򲻽磬ĿǰؽϺãЩƽٽнҲ١

    7 SLE߿Ի

    SLEŮԷߣSLEڼĸʼʼߣ20 ڱΪǻеĽɡŮSLEߵ SLE ͬŮûв13ݣҽѧSLEˮƽߣԼΧڹļǿSLEϲĻĸӤֵõ˼ĸƣSLEȻǽɡ

    ǶSLEߣǰڷʪ߿飬ͬʱſԿ

    ٲ鲻ұȶ6£

    ƤʼصʹüΪ15 mgd൱£

    24h򵰰׶0.5g£

    Ҫ𺦣

    ͣҩ绷װʡ׹ٵ6£

    ûзڼ䲻õҩǰһֱ୵Ļ߽ڼʹá

    SLEڷʪ߿ƺ͸ΣڽѧʵҼ飬мѪѹ24h򵰰סܡڲߣҩƷάֲȶӶǰڵȲ֢ķ

    ȻSLEӰ쵽ķ棬ҲùڵģʱҽͨҪ뵱ȻԼõģ

    οף

    [1]ӢȾİȫԼⷽоչй־200616888-890

    [2]Hardy CJPalmer BPMuir KRet a1Systemic lupus erythe matosus (SLE)and hair treatmenta large community based casecontrol studyLupus19998

    [3]Freni-Titulaer LWJKelley DBGrow AGet alConnective tissue disease in southeastern Georgiaa case control study of etiological factorsAm J Epidemiol1989130404-409

    [4]Cooper GSDooley MATreadwell ELet alSmoking and use of hair treatments in relation to risk of developing systemic lupus erythemat0susJ Rheumatol2001282653.

    [5]Petri MAllhritton J.Hair product use in systemic lupus erythe matosusa case-control studyArthritis Rheum199235625 629

    [6]Jim6nez-Alonso JSabio JMPerez-Alvarez Fet alHair dye treatment use and clinical couFse in patients with systemic lupus erythematosus and cutaneous lupusLupus2002.

    [7]Luijten RKFritsch-Stork RDBijlsma JWet al.The use of gucocorticoids in systemic lupus erythematosus.After 60 years still more an art than sciencel [J]AutoimmunRev201312(5)617-628

    [8].Ѫ岹 C3C4ˮƽϼϵͳ Ǵжȼ[J.йʵҽ20184521115.

    [9]ȫ.Ѫ AnuA dsDNA塢 C1qˮƽϼ ϵͳԺǴϼֵJ.ҽѧо2019281630143016.

    [10]޼ Ҷ . ENAҺ߼ϵͳ ԺǴеļֵо . ҽҩ۴ 2019 17(11)187-188.

    [11]Ӣ . 򵰰׼IJⶨϵͳԺǴе . ʼҽѧ־ 2013(2)225-226.

    [12] ӳ . ϵͳԺǴ벹 . ʼҽѧ־ 2017 38(23)3354-3356.

    [13]йϵͳԺǴоЭר. йϵ ͳԺǴΧڹJ. лҽѧ־201595141056-1060

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